Conformational Preference of Potassium Salts of N-Acylhydrazinecarbodithioates with Antifungal Activity. Combined Experimental and Theoretical Approach

ISSN: 1875-6697 (Online)
ISSN: 1573-4099 (Print)


Volume 10, 4 Issues, 2014


Download PDF Flyer




Current Computer-Aided Drug Design

Aims & ScopeAbstracted/Indexed in

Ranking and Category:
  • 25th of 102 in Computer Science, Interdisciplinary Applications

Submit Abstracts Online Submit Manuscripts Online

Editor-in-Chief:
Subhash C. Basak
Departments of Chemistry, Biochemistry & Molecular Biology University of Minnesota Duluth
Duluth, MN 55811
USA


View Full Editorial Board

Subscribe Purchase Articles Order Reprints

Current: 1.942
5 - Year: 1.885

Conformational Preference of Potassium Salts of N-Acylhydrazinecarbodithioates with Antifungal Activity. Combined Experimental and Theoretical Approach

Author(s): Agata Siwek, Tomasz Plech, Nazar Trotsko, Urszula Kosikowska, Anna Malm, Katarzyna Dzitko and Piotr Paneth

Affiliation: Institute of Applied Radiation Chemistry, Technical University of Lodz, Zeromskiego 116, 90-924 Lodz, Poland

Abstract

In vitro antifungal potency of a set of potassium N-acylhydrazinecarbodithioates was tested. Some of studied salts displayed significant antifungal activity against Candida spp. at non-toxic concentration indicating a high selectivity of their anticandidal activity. In further study, on the example of conformational analysis, we have tested several force fields and semiempirical parametrizations in order to identify those that could be effectively used for modeling of this class of compounds


Purchase Online Rights and Permissions

  
  



Article Details

Volume: 10
First Page: 1
Page Count: 1
DOI: 10.2174/1573409910666140521152701
Advertisement

Related Journals




Webmaster Contact: urooj@benthamscience.org Copyright © 2014 Bentham Science