A 2D Pattern Matching Algorithm for Comparing Primary Protein Sequences

ISSN: 2212-392X (Online)
ISSN: 1574-8936 (Print)

Volume 10, 5 Issues, 2015

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Current Bioinformatics

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Alessandro Giuliani
Istituto Superiore di Sanit√° (Italian NIH) Environment and Health Dept

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A 2D Pattern Matching Algorithm for Comparing Primary Protein Sequences

Current Bioinformatics, 9(3): 210-217.

Author(s): Guohua Huang, Weiping Huang, Wenping Xie, Yongfan Li, Lixin Xu and Houqing Zhou.

Affiliation: Department of Mathematics, Shaoyang University, Shaoyang, Hunan 422000, China.


Sequence comparison in the form of alignment plays a crucial role in the area of bioinformatics. However, alignment is commonly restricted by the number of aligned sequences. To address this problem, we presented a 2D pattern matching algorithm for comparing protein sequences. The new algorithm which is an alignment-free comparison is capable of allowing fast comparison even among a large number of protein sequences. The simulation on the artificial sequences indicated that our method would be robust. And the experiment on real protein sequences showed that our method would be effective.


Alignment, alignment-free comparison, binary tree, graphical representation, phylogenetic tree, sequence, similarity distance.

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Article Details

Volume: 9
Issue Number: 3
First Page: 210
Last Page: 217
Page Count: 8
DOI: 10.2174/1574893609666140516005556

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