Comparative Genomics and Systems Biology of Malaria Parasites Plasmodium

ISSN: 2212-392X (Online)
ISSN: 1574-8936 (Print)

Volume 11, 5 Issues, 2016

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Current Bioinformatics

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Yi-Ping Phoebe Chen
Department of Computer Science and Information Technology
La Trobe University

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Comparative Genomics and Systems Biology of Malaria Parasites Plasmodium

Current Bioinformatics, Volume 8 (E-pub ahead of print)

Author(s): Hong Cai, Zhan Zhou, Jianying Gu and Yufeng Wang.


Malaria is a serious infectious disease that causes over one million deaths yearly. It is caused by a group of protozoan parasites in the genus Plasmodium. No effective vaccine is currently available and the elevated levels of resistance to drugs in use underscore the pressing need for novel antimalarial targets. In this review, we survey omics centered developments in Plasmodium biology, which have set the stage for a quantum leap in our understanding of the fundamental processes of the parasite life cycle and mechanisms of drug resistance and immune evasion.

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Volume: 8
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DOI: 10.2174/15748936113089990016

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