Comparison of Artemisia annua Bioactivities between Traditional Medicine and Chemical Extracts

ISSN: 1875-6646 (Online)
ISSN: 1573-4072 (Print)


Volume 10, 4 Issues, 2014


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Editor-in-Chief:
Adriano Mollica, Ph.D
Department of Pharmacy, University ”G. d' Annunzio” of Chieti-Pescara
Via dei Vestini 31
Chieti, 66100
Italy


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Comparison of Artemisia annua Bioactivities between Traditional Medicine and Chemical Extracts

Author(s): Ahmed Nageeb, Azza Al-Tawashi, Abdul-Hamid Mohammad Emwas, Zeyad Abdel-Halim Al-Talla and Nahla Al-Rifai

Affiliation: Research and Development, Qatar Foundation, PO Box: 5825, Doha Qatar.

Abstract

The present work investigates the efficacy of using Artemisia annua in traditional medicine in comparison with chemical extracts of its bioactive molecules. In addition, the effects of location (Egypt and Jericho) on the bioactivities of the plant were investigated. The results showed that water extracts of Artemisia annua from Jericho have stronger antibacterial activities than organic solvent extracts. In contrast, water and organic solvent extracts of the Artemisia annua from Egypt do not have anti-bacterial activity. Furthermore, while the methanol extract of EA displayed high anticancer affects, the water extract of Egypt and the extracts of Jericho did not show significant anticancer activity. Finally, the results showed that the methanol and water extracts of Jericho had the highest antioxidant activity, while the extracts of Egypt had none. The current results validate the scientific bases for the use of Artemisia annua in traditional medicine. In addition, our results suggest that the collection location of the Artemisia annua has an effect on its chemical composition and bioactivities.

Keywords: Artemisia, bioactivities, NMR, antibacterial, anticancer.

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Article Details

Volume: 9
Issue Number: 4
First Page: 324
Last Page: 332
Page Count: 9
DOI: 10.2174/157340720904140404151439
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