Cells and Mediators of Inflammation in Acute Pancreatitis

ISSN: 2212-7046 (Online)
ISSN: 2212-7038 (Print)

Volume 2, 2 Issues, 2015

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Clinical Anti-Inflammatory & Anti-Allergy Drugs

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Giovanni Passalacqua
Allergy & Respiratory Diseases
Department of Internal Medicine
University of Genova

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Cells and Mediators of Inflammation in Acute Pancreatitis

Author(s): Ramesh Kumar and Madhav Bhatia

Affiliation: Department of Biochemistry, Bundelkhand University, Jhansi (U.P.), India.


Acute pancreatitis (AP) is an acute inflammatory process of the pancreas which involves a complex cascade of events initializing in pancreatic acinar cells. This, in turn leads to an inflammatory response, which results in the pathology of acute pancreatitis. In this review, we describe the role of different cell types and inflammatory mediators in the pathogenesis of acute pancreatitis.

Keywords: Acute pancreatitis, adhesion molecules, cells, chemokines, complements, cytokines, hydrogen sulphide, inflammation, substance P, Toll-like receptors, transcription factors.

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Article Details

Volume: 1
Issue Number: 1
First Page: 11
Last Page: 23
Page Count: 13
DOI: 10.2174/2212703801999131206110914

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