Mini-Review: Polyamines Metabolism, Toxicity and Potent Therapeutical Use

ISSN: 2211-3533 (Online)
ISSN: 2211-3525 (Print)

Volume 13, 2 Issues, 2015

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Anti-Infective Agents

Formerly: Anti-Infective Agents in Medicinal Chemistry

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Mini-Review: Polyamines Metabolism, Toxicity and Potent Therapeutical Use

Author(s): Lamia Djouhri-Bouktab, Jean M. Rolain and Jean M. Brunel

Affiliation: Centre de Recherche en Cancérologie de Marseille (CRCM), CNRS, UMR7258; Institut Paoli Calmettes; Aix-Marseille Université, UM 105; Inserm, U1068, F-13009, Marseille, France.


In recent years, extensive researches have emphasized the fact that polyamines conjugates acting as possessing antitumor, antimicrobial candidates are becoming important in the biogical and medicinal field. In this review, a general design strategy of polyamine conjugates as well as recent progress in both fundamental mechanism studies and potent therapeutic use as anti infectious agents are provided for the readers.

Keywords: Anticancer activity, antimicrobial activity, metabolism, polyamines, therapeutical use.

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Article Details

Volume: 12
Issue Number: 1
First Page: 95
Last Page: 103
Page Count: 9
DOI: 10.2174/22113525113119990118

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