Mini-Review: Polyamines Metabolism, Toxicity and Potent Therapeutical Use

ISSN: 2211-3533 (Online)
ISSN: 2211-3525 (Print)


Volume 12, 2 Issues, 2014


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Anti-Infective Agents

Formerly: Anti-Infective Agents in Medicinal Chemistry

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Mini-Review: Polyamines Metabolism, Toxicity and Potent Therapeutical Use

Author(s): Lamia Djouhri-Bouktab, Jean M. Rolain and Jean M. Brunel

Affiliation: Centre de Recherche en Cancérologie de Marseille (CRCM), CNRS, UMR7258; Institut Paoli Calmettes; Aix-Marseille Université, UM 105; Inserm, U1068, F-13009, Marseille, France.

Abstract

In recent years, extensive researches have emphasized the fact that polyamines conjugates acting as possessing antitumor, antimicrobial candidates are becoming important in the biogical and medicinal field. In this review, a general design strategy of polyamine conjugates as well as recent progress in both fundamental mechanism studies and potent therapeutic use as anti infectious agents are provided for the readers.

Keywords: Anticancer activity, antimicrobial activity, metabolism, polyamines, therapeutical use.

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Article Details

Volume: 12
Issue Number: 1
First Page: 95
Last Page: 103
Page Count: 9
DOI: 10.2174/22113525113119990118
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