Microtubule-targeting Anticancer Agents from Marine Natural Substance

ISSN: 1875-5992 (Online)
ISSN: 1871-5206 (Print)


Volume 14, 10 Issues, 2014


Download PDF Flyer




Anti-Cancer Agents in Medicinal Chemistry

Formerly: Current Medicinal Chemistry - Anti-Cancer Agents

Aims & ScopeAbstracted/Indexed in

Ranking and Category:
  • 26th of 59 in Chemistry, Medicinal
  • 99th of 197 in Oncology

Submit Abstracts Online Submit Manuscripts Online

Editor-in-Chief:
Michelle Prudhomme
Universite Blaise Pascal - C.N.R.S
Aubiere Cedex
France


View Full Editorial Board

Subscribe Purchase Articles Order Reprints

Current: 2.61

Microtubule-targeting Anticancer Agents from Marine Natural Substance

Author(s): Zhiguo Liu, Pengfei Xu, Tao Wu and Wenbin Zeng

Affiliation: School of Pharmaceutical Sciences, Central South University, Changsha 410013, China

Abstract

Effective novel therapeutics is urgently needed due to increasing incidence of malignant cancer and drug multi-resistance. Natural products and their derivatives have historically been a source of pharmaceutical leads and therapeutic drugs. Microtubuletargeting compounds are among the most promising candidates in the combat against cancer. In particular, marine natural products (MNPs) have demonstrated exceptional potency and potential as anticancer agents. Drug discovery from MNPs provides a new pathway to develop original anticancer agents. In this review, seven classes of typical MNPs with diverse structures are summarized. Bioactive marine compounds isolated from different organisms including invertebrate animals, algae, fungi and bacteria are also discussed.

Keywords: Anticancer, marine, microtubule, natural products.

Purchase Online Rights and Permissions

Article Details

Volume: 14
Issue Number: 3
First Page: 409
Last Page: 417
Page Count: 9
DOI: 10.2174/187152061403140207163402
Advertisement


Webmaster Contact: urooj@benthamscience.org Copyright © 2014 Bentham Science