Osteoarthritis (OA) affects millions of people worldwide. However, there is
no consensus on the treatment of OA. Treatments aim to reduce pain and help joint
function. But they only improve symptoms in the medium term. Nowadays, we have
diverse intra-articular treatments, which aim to get better results. Viscosupplementation
and Platelet rich plasma are based on the physiologic relevance of hyaluronic acid in
synovial joints, and the effect of platelets in the intra-articular homeostasis
respectively. HA is used with good results in young patients with Knee OA grade I-II.
Additionally, there is enough evidence to consider the PRP as a valid and effective
treatment to reduce pain and to improve the quality of life of patients with knee OA.
Keywords: Hip osteoarthritis, Hyaluronic acid, Knee osteoarthritis, Platelet rich
plasma, Viscosupplementation and growth factors.